Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Friday, August 1, 2014

Platelets: crossroads of immunity and hemostasis

Koupenova and colleagues report that platelets express functional TOLL-like receptor 7 (TLR7) and contribute to host survival during viral infection. Through a series of experiments utilizing mice deficient for TLR7 together with adoptive transfer of wild-type platelets, Koupenova et al demonstrate that platelets specifically respond to viral analogs and intact virus, leading to platelet activation and binding to various leukocyte subsets. Perhaps most importantly, this platelet activation appears absolutely essential for host survival during infection with some viral pathogens such as encephalomyocarditis virus (EMCV).

Read more:
Platelets: crossroads of immunity and hemostasis



















Source: Blood magazine

No comments:

Follow "Art and Science of Laboratory Medicine " on:


https://www.facebook.com/LaboratoryEQAS
https://twitter.com/LaboratoryEQAS
https://plus.google.com/100408138227362094524/posts
http://www.pinterest.com/labmed/medical-laboratory-and-biomedical-science/
http://www.linkedin.com/in/jwahlstedt
http://clinical-laboratory.blogspot.com/feeds/posts/default