Art and Science of Laboratory Medicine

Art and Science of Laboratory Medicine

Sunday, December 4, 2016

From path with love

Amasing histology slide

Original image:
Good morning

Source: Facebook via Trust me I´m a "Medical Technologist"

The Never-ending Mannequin Challenge

 Every day is a mannequin challenge for ALS patients.

View in YouTube:
The never-ending Mannequin Challenge

Source: YouTube

Missing Link in Malaria Evolution Discovered in Historical Specimens

A family’s collection of antique microscope slides became a trove of genetic information about the eradicated European malaria pathogen. These slides of stained blood droplets date to the 1940s and contain strains of the malaria parasite that are now extinct (image).

Lalueza-Fox and his colleagues were left with the first genetic material of extinct European Plasmodium species ever studied. They recovered DNA from both P. falciparum, the predominant species in Africa and the species responsible for the majority of today’s malaria deaths, and P. vivax, a less virulent species found widely across the globe. Scientists have long debated how P. vivax arrived in the Americas, with one theory suggesting colonial Europeans brought the pathogen over, while another posits entry from the other direction, when early humans crossed the Bering Land Bridge from Asia. The two theories, notes Jane Carlton, a malaria researcher at New York University who was not involved in the study, are not necessarily mutually exclusive.

The extinct European P. vivax genome more closely resembled strains found today in South America than those found in East Asia, lending credibility to the theory of a more recent introduction by European colonists. The European P. falciparum genome, however, was starkly divergent from the modern South American subtype, supporting the theory that this more-deadly species came to South America directly from Africa during the slave trade.

Read more:
Missing Link in Malaria Evolution Discovered in Historical Specimens

Source: The Scientist Magazine®
Image: Charles Aranda

Saturday, December 3, 2016

Cat people have meowcytes in their blood

Peripheral blood cell morphology. Meowcyte by Theresa Gonzales

Source: Facebook via Theresa Gonzalez

Where to test HIV or Hepatitis? - European Test Finder

 Almost every second person (47%) diagnosed in 2014 was a late presenter or with indication of advanced infection. This means that these individuals are only diagnosed when their immune system already starts to fail. Providing antiretroviral therapy at the early stages of HIV infection allows people with HIV to live longer and healthier lives, and reduces the risk of transmitting HIV to others.

With the newly created and mobile-optimised European Test Finder, it only takes a few seconds to locate a testing site near you – wherever you are in Europe.

Open search engine here:
European test finder

Source: ECDC

Hospital command center

The people who manage patient flow at hospitals might like a crystal ball that shows them when their resources are about to be overwhelmed. Hospitals are trying out what might be the next best thing. They're wiring command centers with monitors that display predictive analytics fueled by every conceivable data source that gives a glimpse of a patient's movement through the facility.

Taking a cue from other industries that assemble command centers to manage complex logistics, GE Healthcare equipped Johns Hopkins with the company's first Wall of Analytics, which features 22 information screens that can pull data from 14 sources, including the electronic health record, admission software and OR scheduling applications. GE is working with a handful of other hospitals to deploy the technology.

Although the command center at Johns Hopkins has been up and running for less than a year, the hospital has seen a 30% reduction in ER patients who have to wait for an inpatient bed and a roughly 70% reduction in patients who must be held in the OR because there's no recovery or inpatient bed for them, according to Jim Scheulen, Johns Hopkins Hospital's chief administrative officer for emergency medicine and capacity management.

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Hospital command centers help manage flow

Source: Modern Healthcare Modern Healthcare business news

Friday, December 2, 2016

New method to restore function of white blood cells in septic patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

"We hope that this study will lead to a better understanding of why patients with sepsis are often unable to successfully eradicate invading microorganisms," said author Andriani C. Patera, Ph.D. "Furthermore, we hope that this study will stimulate new therapies to treat sepsis based on stimulating various components of the immune system."

Read more:
Scientists discover new method to restore function of white blood cells in septic patients

Source: EurekAlert! Science News

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